86-4045-29　［取扱停止］Phospho-Estrogen Receptor alpha(S118) Polyclonal Antibody 200uL　E-AB-68097

特徴

• 背景：This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.

仕様

• 抗体タイプ：Phosphorylated antibody
• アプリケーション：IHC,IF
• 交差性：Human
• 宿主：Rabbit
• アイソタイプ：IgG
• 抗原：A phospho specific peptide corresponding to residues surrounding S118 of human Estrogen Receptor alpha
• 緩衝液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• 精製方法：Affinity purification
• 希釈倍率：IHC 1:50-1:100 IF 1:100-1:200
• 標識：Unconjugated
• メーカーマニュアル：https://file.elabscience.com/viewpdf-391349-Elabscience-E-AB-68097.pdf
• サイズ：200uL
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