86-4043-73　AF/LE Purified Anti-Human CD274/PD-L1 Antibody[29E.2A3] 1mg　E-AB-F11330

特徴

• 背景：CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.

仕様

• 抗体タイプ：FC_Antibody
• アプリケーション：Block, FA, FCM, IHC
• 交差性：Human
• 宿主：Mouse
• アイソタイプ：Mouse IgG2b, kappa
• 緩衝液：0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
• 標識：None (Purified antibody-Azide Free/Low endotoxin)
• クローナリティ：Monoclonal
• メーカーマニュアルリンク：https://file.elabscience.com/viewpdf-176606-Elabscience-E-AB-F11330.pdf
• サイズ：1mg
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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