86-4041-95　［取扱停止］PE/Cyanine7 Anti-Mouse CD115 Antibody[AFS98] 500 Tests　E-AB-F1107H

特徴

• 背景：CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene) gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitination of intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts.

仕様

• 抗体タイプ：FC_Antibody
• アプリケーション：FCM
• 交差性：Mouse
• 宿主：Rat
• アイソタイプ：Rat IgG2a, kappa
• 緩衝液：PBS with 0.05% Proclin300, 1% BSA
• 標識：PE/Cyanine7
• クローナリティ：Monoclonal
• メーカーマニュアルリンク：https://file.elabscience.com/viewpdf-376694-Elabscience-E-AB-F1107H.pdf
• サイズ：500 Tests
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