86-4041-22　［取扱停止］HLA-DMB Polyclonal Antibody 200uL　E-AB-67981

特徴

• 背景：HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.

仕様

• 抗体タイプ：Polyclonal Antibody
• アプリケーション：IHC
• 交差性：Human
• 宿主：Rabbit
• アイソタイプ：IgG
• 抗原：Recombinant fusion protein of human HLA-DMB (NP_002109.2).
• 緩衝液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• 精製方法：Affinity purification
• 希釈倍率：IHC 1:50-1:100
• 標識：Unconjugated
• メーカーマニュアル：https://file.elabscience.com/viewpdf-391233-Elabscience-E-AB-67981.pdf
• サイズ：200uL
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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