86-4040-36　［取扱停止］CA8 Polyclonal Antibody 200uL　E-AB-67887

特徴

• 背景：The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in this gene are associated with cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3). Polymorphisms in this gene are associated with osteoporosis, and overexpression of this gene in osteosarcoma cells suggests an oncogenic role. Alternative splicing results in multiple transcript variants.

仕様

• 抗体タイプ：Polyclonal Antibody
• アプリケーション：IHC
• 交差性：Human,Mouse
• 宿主：Rabbit
• アイソタイプ：IgG
• 抗原：Recombinant fusion protein of human CA8 (NP_004047.3).
• 緩衝液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• 精製方法：Affinity purification
• 希釈倍率：IHC 1:50-1:200
• 標識：Unconjugated
• メーカーマニュアル：https://file.elabscience.com/viewpdf-391139-Elabscience-E-AB-67887.pdf
• サイズ：200uL
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