特徴
- 背景:This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
仕様
- 抗体タイプ:Polyclonal Antibody
- アプリケーション:WB,IHC
- 交差性:Mouse,Rat
- 宿主:Rabbit
- アイソタイプ:IgG
- 抗原:Recombinant fusion protein of human FBXO32 (NP_478136.1).
- 緩衝液:PBS with 0.02% sodium azide, 50% glycerol, pH7.3
- 精製方法:Affinity purification
- 希釈倍率:WB 1:1000-1:2000 IHC 1:50-1:200
- 標識:Unconjugated
- メーカーマニュアル:https://file.elabscience.com/viewpdf-390817-Elabscience-E-AB-67565.pdf
- サイズ:200uL
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- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
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- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-4002-15
FBXO32 Polyclonal Antibody 120uL
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86-3956-29
FBXO32 Polyclonal Antibody 60uL
|
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86-4037-39
FBXO32 Polyclonal Antibody 200uL
|
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