特徴
- 背景:The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported./The protein encoded by this gene is a member of the MAP kinase family.
仕様
- 抗体タイプ:Polyclonal Antibody
- アプリケーション:WB
- 交差性:Human,Mouse,Rat
- 宿主:Rabbit
- アイソタイプ:IgG
- 抗原:Recombinant protein of human JNK1/2.
- 緩衝液:PBS with 0.02% sodium azide, 50% glycerol, pH7.3
- 精製方法:Affinity purification
- 希釈倍率:WB 1:500-1:2000
- 標識:Unconjugated
- メーカーマニュアル:https://file.elabscience.com/viewpdf-390587-Elabscience-E-AB-67335.pdf
- サイズ:200uL
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
- FAX:06-6447-8642
- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-4000-54
JNK1/2 Polyclonal Antibody 120uL
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86-3954-69
JNK1/2 Polyclonal Antibody 60uL
|
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86-4035-78
JNK1/2 Polyclonal Antibody 200uL
|
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掲載カタログ情報
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