86-4035-47　［取扱停止］RUNX1T1 Polyclonal Antibody 200uL　E-AB-67119

特徴

• 背景：This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants.

仕様

• 抗体タイプ：Polyclonal Antibody
• アプリケーション：WB
• 交差性：Human
• 宿主：Rabbit
• アイソタイプ：IgG
• 抗原：Recombinant fusion protein of human RUNX1T1 (NP_783554.1).
• 緩衝液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• 精製方法：Affinity purification
• 希釈倍率：WB 1:200-1:1000
• 標識：Unconjugated
• メーカーマニュアル：https://file.elabscience.com/viewpdf-390371-Elabscience-E-AB-67119.pdf
• サイズ：200uL
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