86-4035-08　［取扱停止］CYP27B1 Polyclonal Antibody 200uL　E-AB-67067

特徴

• 背景：This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I.

仕様

• 抗体タイプ：Polyclonal Antibody
• アプリケーション：WB,IF
• 交差性：Human,Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 抗原：Recombinant fusion protein of human CYP27B1 (NP_000776.1).
• 緩衝液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• 精製方法：Affinity purification
• 希釈倍率：WB 1:500-1:2000 IF 1:20-1:50
• 標識：Unconjugated
• メーカーマニュアル：https://file.elabscience.com/viewpdf-390319-Elabscience-E-AB-67067.pdf
• サイズ：200uL
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