86-4032-88　［取扱停止］FADD Polyclonal Antibody 200uL　E-AB-66826

特徴

• 背景：The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.

仕様

• 抗体タイプ：Polyclonal Antibody
• アプリケーション：WB,IF
• 交差性：Mouse,Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 抗原：Recombinant protein of human FADD
• 緩衝液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• 精製方法：Affinity purification
• 希釈倍率：WB 1:500-1:2000 IF 1:50-1:200
• 標識：Unconjugated
• メーカーマニュアル：https://file.elabscience.com/viewpdf-390078-Elabscience-E-AB-66826.pdf
• サイズ：200uL
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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