86-4032-53　［取扱停止］IFI35 Polyclonal Antibody 200uL　E-AB-66789

特徴

• 背景：The Interferon family of proteins are able to alter the expression of a variety of target genes, thereby controlling various events within the cell. IFI-35 (Interferon-induced 35 kDa protein), also known as IFP35, is a 286 amino acid interferon-induced protein. Localized to the nucleus and expressed in macrophages, fibroblasts and epithelial cells, IFI-35 is a leucine zipper protein that can form homodimers, but, unlike most leucine zipper proteins, cannot bind DNA. Upon induction by IFN-α, IFI-35 associates with Nmi (N-Myc-interacting protein), resulting in the formation of a high molecular weight complex that is thought to play a role in IFN-α signaling and cellular responses. Once complexed with Nmi, IFI-35 is unable to be degraded by the proteasome, suggesting that IFI-35 is protected from degradation only when needed by IFN-α. Two isoforms of IFI-35 exist due to alternative splicing events.

仕様

• 抗体タイプ：Polyclonal Antibody
• アプリケーション：WB
• 交差性：Human,Mouse
• 宿主：Rabbit
• アイソタイプ：IgG
• 抗原：Recombinant fusion protein of human IFI35 (NP_005524.2).
• 緩衝液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• 精製方法：Affinity purification
• 希釈倍率：WB 1:500-1:2000
• 標識：Unconjugated
• メーカーマニュアル：https://file.elabscience.com/viewpdf-390041-Elabscience-E-AB-66789.pdf
• サイズ：200uL
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