特徴
- 背景:TAZ, also referred as WWTR1, is a transcriptional co-activator with a PDZ-binding motif that is regulated by its interaction with 14-3-3 protein. TAZ is expressed in many primary tumors, such as breast cancer, thyroid carcinoma, colorectal cancer, and glioma. TAZ has been reported to be one of the nuclear effectors of Hippo-related pathways that regulate organ size control, cancer stem cell (CSC) properties, and epithelial–mesenchymal transition (EMT). TAZ has been defined for its role in the nucleus, where it functions directly as a transcriptional regulator by interacting with several nuclear factors as Runx2/Cbfa1, NHERF-2, TEF-1, TBX5, PAX3, PAX8 and TTF-1.
仕様
- 抗体タイプ:Polyclonal Antibody
- アプリケーション:IF
- 交差性:Human,Mouse
- 宿主:Rabbit
- アイソタイプ:IgG
- 抗原:A synthetic peptide of human TAZ (NP_056287.1).
- 緩衝液:PBS with 0.02% sodium azide, 50% glycerol, pH7.3
- 精製方法:Affinity purification
- 希釈倍率:IF 1:50-1:200
- 標識:Unconjugated
- メーカーマニュアル:https://file.elabscience.com/viewpdf-389838-Elabscience-E-AB-66586.pdf
- サイズ:200uL
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
- FAX:06-6447-8642
- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-4030-78
TAZ Polyclonal Antibody 200uL
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86-3995-54
TAZ Polyclonal Antibody 120uL
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86-3949-70
TAZ Polyclonal Antibody 60uL
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掲載カタログ情報
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