86-4030-37　［取扱停止］PRKAB1 Polyclonal Antibody 200uL　E-AB-66544

特徴

• 背景：The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.

仕様

• 抗体タイプ：Polyclonal Antibody
• アプリケーション：IF
• 交差性：Human
• 宿主：Rabbit
• アイソタイプ：IgG
• 抗原：A synthetic peptide of human PRKAB1 (NP_006244.2).
• 緩衝液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• 精製方法：Affinity purification
• 希釈倍率：IF 1:50-1:200
• 標識：Unconjugated
• メーカーマニュアル：https://file.elabscience.com/viewpdf-389796-Elabscience-E-AB-66544.pdf
• サイズ：200uL
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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