特徴
- 背景:The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene.
仕様
- 抗体タイプ:Polyclonal Antibody
- アプリケーション:WB
- 交差性:Human,Mouse
- 宿主:Rabbit
- アイソタイプ:IgG
- 抗原:Recombinant fusion protein of human PTPRJ (NP_002834.3).
- 緩衝液:PBS with 0.02% sodium azide, 50% glycerol, pH7.3
- 精製方法:Affinity purification
- 希釈倍率:WB 1:200-1:1000
- 標識:Unconjugated
- メーカーマニュアル:https://file.elabscience.com/viewpdf-388993-Elabscience-E-AB-65741.pdf
- サイズ:200uL
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
- FAX:06-6447-8642
- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-3987-47
PTPRJ Polyclonal Antibody 120uL
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86-4022-71
PTPRJ Polyclonal Antibody 200uL
|
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86-3941-68
PTPRJ Polyclonal Antibody 60uL
|
よくあるご質問(FAQ)
掲載カタログ情報
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