86-4022-05　AF/LE Purified Anti-Human CD8a Antibody[OKT-8] 1mg　E-AB-F11100

特徴

• 背景：CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

仕様

• 抗体タイプ：FC_Antibody
• アプリケーション：Depletion, FCM
• 交差性：Human
• 宿主：Mouse
• アイソタイプ：Mouse IgG2a, kappa
• 緩衝液：0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
• 標識：None (Purified antibody-Azide Free/Low endotoxin)
• クローナリティ：Monoclonal
• メーカーマニュアルリンク：https://file.elabscience.com/viewpdf-176595-Elabscience-E-AB-F11100.pdf
• サイズ：1mg
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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