86-4021-85　AF/LE Purified Anti-Mouse CD274/PD-L1 Antibody[10F.9G2] 1mg　E-AB-F11320

特徴

• 背景：CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.

仕様

• 抗体タイプ：FC_Antibody
• アプリケーション：FCM,IHC,IF,Block
• 交差性：Mouse
• 宿主：Rat
• アイソタイプ：Rat IgG2b, kappa
• 緩衝液：0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
• 標識：None (Purified antibody-Azide Free/Low endotoxin)
• クローナリティ：Monoclonal
• メーカーマニュアルリンク：https://file.elabscience.com/viewpdf-208960-Elabscience-E-AB-F11320.pdf
• サイズ：1mg
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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