特徴
- 背景：This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene.
仕様
- 抗体タイプ：Polyclonal Antibody
- アプリケーション：IHC
- 交差性：Human,Mouse,Rat
- 宿主：Rabbit
- アイソタイプ：IgG
- 抗原：Recombinant Human GTPase HRas protein
- 緩衝液：PBS with 0.05% Proclin300, 50% glycerol, pH7.3
- 精製方法：Antigen Affinity Purification
- 希釈倍率：IHC 1:100-1:300
- 標識：Unconjugated
- クローナリティ：Polyclonal
- メーカーマニュアル：https://file.elabscience.com/viewpdf-447077-Elabscience-E-AB-40406.pdf
- サイズ：200uL
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
|
86-3985-66
HRAS Polyclonal Antibody 120uL
|
|
|
86-4020-77
HRAS Polyclonal Antibody 200uL
|
よくあるご質問（FAQ）
掲載カタログ情報
| 掲載カタログ名 | 掲載ページ |
|---|