86-4018-69　［取扱停止］AF/LE Purified Anti-Human CD279/PD-1 Antibody[J116] 500ug　E-AB-F11290

特徴

• 背景：Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 (B7-H1) and PD-L2 (B7-DC) are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.

仕様

• 抗体タイプ：FC_Antibody
• アプリケーション：Block, Neut, FCM,IHC,IP
• 交差性：Human
• 宿主：Mouse
• アイソタイプ：Mouse IgG1, kappa
• 緩衝液：0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
• 標識：None (Purified antibody-Azide Free/Low endotoxin)
• クローナリティ：Monoclonal
• メーカーマニュアルリンク：https://file.elabscience.com/viewpdf-178513-Elabscience-E-AB-F11290.pdf
• サイズ：500ug
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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