86-4018-45　［取扱停止］AF/LE Purified Anti-Mouse CD279/PD-1 Antibody[29F.1A12] 500ug　E-AB-F11310

特徴

• 背景：CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.

仕様

• 抗体タイプ：FC_Antibody
• アプリケーション：Block, Neut, FCM, WB, IHC, IF
• 交差性：Mouse
• 宿主：Rat
• アイソタイプ：Rat IgG2a, kappa
• 緩衝液：0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
• 標識：None (Purified antibody-Azide Free/Low endotoxin)
• クローナリティ：Monoclonal
• メーカーマニュアルリンク：https://file.elabscience.com/viewpdf-176605-Elabscience-E-AB-F11310.pdf
• サイズ：500ug
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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