特徴
- 背景:This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
仕様
- 抗体タイプ:Phosphorylated antibody
- アプリケーション:IF
- 交差性:Human
- 宿主:Rabbit
- アイソタイプ:IgG
- 抗原:A synthetic phosphorylated peptide around Y319 of human ZAP70 (NP_001070.2).
- 緩衝液:PBS with 0.02% sodium azide, 50% glycerol, pH7.3
- 精製方法:Affinity purification
- 希釈倍率:IF 1:50-1:200
- 標識:Unconjugated
- メーカーマニュアル:https://file.elabscience.com/viewpdf-391405-Elabscience-E-AB-68153.pdf
- サイズ:120uL
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
- FAX:06-6447-8642
- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-3982-21
Phospho-ZAP70(Y319) Polyclonal Antibody 60uL
|
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86-4017-85
Phospho-ZAP70(Y319) Polyclonal Antibody 120uL
|
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86-4045-81
Phospho-ZAP70(Y319) Polyclonal Antibody 200uL
|
よくあるご質問(FAQ)
掲載カタログ情報
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