86-4013-45　［取扱停止］APC Anti-Human CD197/CCR7 Antibody[G043H7] 100*2Tests　E-AB-F1159E

特徴

• 背景：CCR7, also known as CD197, is a chemokine receptor that binds CCL19 and CCL21. CCR7 and its ligands link innate and adaptive immunity by affecting interactions between T cells and dendritic cells and their downstream effect. Nave T cells enter the lymph node through high endothelial venules, which express CCL21. Dendritic cells and macrophages enter the lymph node through afferent lymphatics. The encounter of T cells and dendritic cells in the T cell zone is CCR7-dependent. In addition, during immunological surveillance, B cells recirculate between B-cell-rich compartments (follicles or B cell zones) in secondary lymphoid organs, surveying for antigen. After antigen binding, B cells move to the boundary of B and T zones to interact with T-helper cells; this B cell migration is directed by CCR7 and its ligands. CCR7-positive cancer cell expression has been associated with lymph node metastasis. Product Details

仕様

• 抗体タイプ：FC_Antibody
• アプリケーション：FCM
• 交差性：Human
• 宿主：Mouse
• アイソタイプ：Mouse IgG2a, kappa
• 緩衝液：PBS with 0.05% Proclin300, 1% BSA
• 標識：APC
• クローナリティ：Monoclonal
• メーカーマニュアルリンク：https://file.elabscience.com/viewpdf-172793-Elabscience-E-AB-F1159E.pdf
• サイズ：200Tests
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