86-4012-05　［取扱停止］Anti-MERS-CoV Nucleocapsid Monoclonal Antibody 50uL　E-AB-V1281

特徴

• 背景：Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

仕様

• アプリケーション：WB,ELISA
• 交差性：MERS-CoV
• 宿主：Mouse
• アイソタイプ：IgG1
• 抗原：Recombinant MERS-CoV Nucleoprotein / NP protein (His Tag)
• 緩衝液：0.2 μm filtered solution in PBS
• 精製方法：Protein A Affinity
• 希釈倍率：WB 1:1000-1:5000
• 標識：Unconjugated
• メーカーマニュアルリンク：https://file.elabscience.com/viewpdf-457036-Elabscience-E-AB-V1281.pdf
• サイズ：50uL
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