86-4001-13　［取扱停止］DCTN2 Polyclonal Antibody 120uL　E-AB-67423

特徴

• 背景：This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

仕様

• 抗体タイプ：Polyclonal Antibody
• アプリケーション：WB,IHC,IF
• 交差性：Human,Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 抗原：Recombinant fusion protein of human DCTN2 (NP_006391.1).
• 緩衝液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• 精製方法：Affinity purification
• 希釈倍率：WB 1:500-1:2000 IHC 1:50-1:200 IF 1:20-1:50
• 標識：Unconjugated
• メーカーマニュアル：https://file.elabscience.com/viewpdf-390675-Elabscience-E-AB-67423.pdf
• サイズ：120uL
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