特徴
- 背景:This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.
仕様
- 抗体タイプ:Polyclonal Antibody
- アプリケーション:IHC
- 交差性:Human,Mouse,Rat
- 宿主:Rabbit
- アイソタイプ:IgG
- 抗原:Recombinant fusion protein of human IL4R (NP_000409.1).
- 緩衝液:PBS with 0.02% sodium azide, 50% glycerol, pH7.3
- 精製方法:Affinity purification
- 希釈倍率:IHC 1:50-1:200
- 標識:Unconjugated
- メーカーマニュアル:https://file.elabscience.com/viewpdf-389572-Elabscience-E-AB-66320.pdf
- サイズ:120uL
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
- FAX:06-6447-8642
- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-4028-23
IL4R Polyclonal Antibody 200uL
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86-3992-98
IL4R Polyclonal Antibody 120uL
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86-3947-15
IL4R Polyclonal Antibody 60uL
|
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掲載カタログ情報
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