特徴
- 背景：TMEM16A, also known as DOG1, ORAOV2, TAOS2 or ANO1 (anoctamin 1), is a 986 amino acid multi-pass membrane protein that localizes to both the cell membrane and the cytoplasm and belongs to the anoctamin family. Expressed in a variety of tissues with highest expression in skeletal muscle and liver, TMEM16A functions as a calcium-activated chloride channel that is required for normal tracheal development. Human TMEM16A shares 90% sequence identity with its mouse counterpart, suggesting a conserved role between species. TMEM16A is present in breast, pancreatic, gastric, and uterine cancers, as well as in neck, ovarian and parathyroid tumors, suggesting a role for TMEM16A in carcinogenesis. Three isoforms of TMEM16A exist due to alternative splicing events.
仕様
- 抗体タイプ：Polyclonal Antibody
- アプリケーション：IF
- 交差性：Human,Mouse,Rat
- 宿主：Rabbit
- アイソタイプ：IgG
- 抗原：Recombinant fusion protein of human ANO1 (NP_060513.5).
- 緩衝液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3
- 精製方法：Affinity purification
- 希釈倍率：IF 1:100-1:200
- 標識：Unconjugated
- メーカーマニュアル：https://file.elabscience.com/viewpdf-389026-Elabscience-E-AB-65774.pdf
- サイズ：120uL
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-4023-02
ANO1 Polyclonal Antibody 200uL
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86-3987-77
ANO1 Polyclonal Antibody 120uL
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86-3941-98
ANO1 Polyclonal Antibody 60uL
|
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掲載カタログ情報
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