背景：T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a gamma and a delta chain (TCR gamma / delta ). TCR gamma / delta belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The TCR gamma / delta associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most gamma / delta T cells are CD4-/CD8-, some are CD8+. T cells expressing the TCR gamma / delta have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that gamma / delta T cells also play a principal role in antigen presentation. Immobilized UC7-13D5 antibody has been reported to activate TCR- gamma / delta -bearing T cells in vitro, and to deplete peripheral TCR- gamma / delta -bearing T cells in vivo.
![FITC Anti-Mouse TCR gamma / delta Antibody[UC7-13D5] 500Tests](https://aimg.as-1.co.jp/c/86/3986/89/86393868.jpg)