特徴
- 背景：S100A4 is a member of the S100 family of calcium-binding proteins. The S100 family members have been involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 is known to localize to and function in the nucleus, cytoplasm of cells and the extracellular space. S100A4 has also been shown to be associated with tumor growth, motility, invasion, metastasis, angiogenesis, apoptosis and chemoresistance. It is a fibroblast-specific protein associated with mesenchymal cell morphology and motility, is expressed during epithelial-mesenchymal transformations (EMT) in vivo. It is an improved marker for lung fibroblasts that could be useful for investigating the pathogenesis of pulmonary fibrosis. Overexpression of S100A4 is correlated with a worse prognosis inpatients with various types of cancer.
仕様
- 抗体タイプ：Polyclonal Antibody
- アプリケーション：IHC
- 交差性：Human,Rat
- 宿主：Rabbit
- アイソタイプ：IgG
- 抗原：Recombinant Human Protein S100-A4 protein
- 緩衝液：PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
- 精製方法：Antigen Affinity Purification
- 希釈倍率：IHC 1:100-1:400
- 標識：Unconjugated
- クローナリティ：Polyclonal
- メーカーマニュアル：https://file.elabscience.com/viewpdf-469108-Elabscience-E-AB-40458.pdf
- サイズ：120uL
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- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-4021-30
S100A4 Polyclonal Antibody 200uL
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86-3986-19
S100A4 Polyclonal Antibody 120uL
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