特徴
- 背景:A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.
仕様
- 抗体タイプ:Polyclonal Antibody
- アプリケーション:WB,IHC
- 交差性:Human,Mouse,Rat
- 宿主:Rabbit
- アイソタイプ:IgG
- 抗原:Recombinant Mouse Breakpoint cluster region protein
- 緩衝液:PBS with 0.05% Proclin300, 50% glycerol, pH7.3
- 精製方法:Antigen Affinity Purification
- 希釈倍率:WB 1:500-1:2000 IHC 1:50-1:200
- 標識:Unconjugated
- クローナリティ:Polyclonal
- メーカーマニュアル:https://file.elabscience.com/viewpdf-447102-Elabscience-E-AB-40431.pdf
- サイズ:120uL
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
- FAX:06-6447-8642
- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-3985-91
BCR Polyclonal Antibody 120uL
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86-4021-03
BCR Polyclonal Antibody 200uL
|
よくあるご質問(FAQ)
掲載カタログ情報
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