86-3985-85　［取扱停止］TGFB2 Polyclonal Antibody 120uL　E-AB-40425

特徴

• 背景：This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1;7)(q41;p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified.

仕様

• 抗体タイプ：Polyclonal Antibody
• アプリケーション：WB,IHC
• 交差性：Human,Mouse,Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 抗原：Recombinant Human Transforming growth factor beta-2 proprotein protein
• 緩衝液：PBS with 0.05% Proclin300, 50% glycerol, pH7.3
• 精製方法：Antigen Affinity Purification
• 希釈倍率：WB 1:500-1:2000 IHC 1:50-1:200
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアル：https://file.elabscience.com/viewpdf-447096-Elabscience-E-AB-40425.pdf
• サイズ：120uL
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