86-3985-53　［取扱停止］FITC Anti-Mouse CD274/PD-L1 Antibody[10F.9G2] 200 ug　E-AB-F1132UC

特徴

• 背景：CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.

仕様

• 抗体タイプ：FC_Antibody
• アプリケーション：FCM
• 交差性：Mouse
• 宿主：Rat
• アイソタイプ：Rat IgG2b, kappa
• 緩衝液：PBS with 0.05% Proclin300, 1% BSA
• 標識：FITC
• クローナリティ：Monoclonal
• メーカーマニュアルリンク：https://file.elabscience.com/viewpdf-385724-Elabscience-E-AB-F1132UC.pdf
• サイズ：200 ug
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