86-3984-69　PE/Cyanine5 Anti-Mouse CD103 Antibody[M290] 100ug　E-AB-F1090UG

特徴

• 背景：CD103 is a type I transmembrane glycoprotein known as αE integrin or Integrin αIEL chain. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. T regulatory cells express high level of CD103. The CD103 expression on lymphocytes can be induced upon activation and TGF-β stimulation. In association with integrin β7, CD103 is expressed as αE/β7 heterodimer. Mature CD103 protein can be cleaved into 2 chains, a 150 kD (C-terminal) chain and a 25 kD (N-terminal) chain, which remain linked by disulfide bonds. CD103 binds to E-cadherin and mediates homing of lymphocytes to the intestinal epithelium.

仕様

• 抗体タイプ：FC_Antibody
• アプリケーション：FCM
• 交差性：Mouse
• 宿主：Rat
• アイソタイプ：Rat IgG2a, kappa
• 緩衝液：PBS with 0.05% Proclin300, 1% BSA
• 標識：PE/Cyanine5
• クローナリティ：Monoclonal
• メーカーマニュアルリンク：https://file.elabscience.com/viewpdf-193057-Elabscience-E-AB-F1090UG.pdf
• サイズ：100ug
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