86-3984-23　［取扱停止］AF/LE Purified Anti-Mouse CD54 Antibody[YN1/1.7.4] 500ug　E-AB-F10180

特徴

• 背景：CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues.

仕様

• 抗体タイプ：FC_Antibody
• アプリケーション：FCM,IF
• 交差性：Mouse
• 宿主：Rat
• アイソタイプ：Rat IgG2b, kappa
• 緩衝液：0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
• 標識：None (Purified antibody-Azide Free/Low endotoxin)
• クローナリティ：Monoclonal
• メーカーマニュアルリンク：https://file.elabscience.com/viewpdf-208936-Elabscience-E-AB-F10180.pdf
• サイズ：500ug
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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