86-3982-49　［取扱停止］Phospho-PKCalpha(S319) Polyclonal Antibody 60uL　E-AB-68183

特徴

• 背景：Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

仕様

• 抗体タイプ：Phosphorylated antibody
• アプリケーション：WB
• 交差性：Human,Mouse,Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 抗原：A synthetic phosphorylated peptide around S319 of human PKCalpha (NP_002728.2).
• 緩衝液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• 精製方法：Affinity purification
• 希釈倍率：WB 1:500-1:2000
• 標識：Unconjugated
• メーカーマニュアル：https://file.elabscience.com/viewpdf-391435-Elabscience-E-AB-68183.pdf
• サイズ：60uL
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