86-3976-79　PE/Cyanine7 Anti-Mouse CD54 Antibody[YN1/1.7.4] 100ug　E-AB-F1018UH

特徴

• 背景：CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues.

仕様

• 抗体タイプ：FC_Antibody
• アプリケーション：FCM
• 交差性：Mouse
• 宿主：Rat
• アイソタイプ：Rat IgG2b, kappa
• 緩衝液：PBS with 0.05% Proclin300, 1% BSA
• 標識：PE/Cyanine7
• クローナリティ：Monoclonal
• メーカーマニュアルリンク：https://file.elabscience.com/viewpdf-192956-Elabscience-E-AB-F1018UH.pdf
• サイズ：100ug
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