86-3975-15　［取扱停止］AF488 Anti-Human CD22 Antibody[BU59] 100 Tests　E-AB-F1047L

特徴

• 背景：CD22 is a 130 kD type I transmembrane glycoprotein also known as Siglec-2 and BL-CAM. It is a member of the immunoglobulin superfamily (sialoadhesion subgroup). CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells. CD22 is present in the B cell receptor complex and associates with SHP-1, Syk, Lck, Lyn, and phospholipase Cγ1. A primary function of CD22 is thought to be in limiting antigen receptor signaling by modulating B cell activation threshold. CD22 has been shown to bind to CD45RO and CD75, although the natural ligands for this molecule remain controversial.

仕様

• 抗体タイプ：FC_Antibody
• アプリケーション：FCM
• 交差性：Human
• 宿主：Mouse
• アイソタイプ：Mouse IgG1, kappa
• 緩衝液：PBS with 0.05% Proclin300, 1% BSA
• 標識：AF488
• クローナリティ：Monoclonal
• メーカーマニュアルリンク：https://file.elabscience.com/viewpdf-134558-Elabscience-E-AB-F1047L.pdf
• サイズ：100 Tests
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