背景:T cell receptor (TCR) is a heterodimer consisting of an alpha and a beta chain (TCR alpha / beta ) or a gamma and a delta chain (TCR gamma / delta ). TCR- beta is a member of the immunoglobulin superfamily and a component of the CD3/TCR complex (along with TCR- alpha ). It is expressed on alpha / beta TCR-bearing T cells and thymocytes. The CD3/TCR complex plays a key role in antigen recognition, signal transduction, and T cell activation.