86-3955-41　［取扱停止］BRCA2 Polyclonal Antibody 60uL　E-AB-67462

特徴

• 背景：Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele.

仕様

• 抗体タイプ：Polyclonal Antibody
• アプリケーション：IF
• 交差性：Human,Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 抗原：Recombinant fusion protein of human BRCA2 (NP_000050.2).
• 緩衝液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• 精製方法：Affinity purification
• 希釈倍率：IF 1:50-1:200
• 標識：Unconjugated
• メーカーマニュアル：https://file.elabscience.com/viewpdf-390714-Elabscience-E-AB-67462.pdf
• サイズ：60uL
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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