86-3952-73　［取扱停止］RHOB Polyclonal Antibody 60uL　E-AB-66931

特徴

• 背景：Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.RHOB is a member of the Rho GTP-binding protein family.Mediates apoptosis in neoplastically transformed cells after DNA damage. It is not necessary for development but affects cell adhesion and growth factor signaling in transformed cells. It plays a negative role in tumorigenesis as deletion causes tumor formation. It involved in intracellular protein trafficking of a number of proteins, and serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.

仕様

• 抗体タイプ：Polyclonal Antibody
• アプリケーション：WB
• 交差性：Mouse
• 宿主：Rabbit
• アイソタイプ：IgG
• 抗原：A synthetic peptide of human RHOB (NP_004031.1).
• 緩衝液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• 精製方法：Affinity purification
• 希釈倍率：WB 1:500-1:2000
• 標識：Unconjugated
• メーカーマニュアル：https://file.elabscience.com/viewpdf-390183-Elabscience-E-AB-66931.pdf
• サイズ：60uL
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