86-3948-06　［取扱停止］LRP6 Polyclonal Antibody 60uL　E-AB-66414

特徴

• 背景：This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.

仕様

• 抗体タイプ：Polyclonal Antibody
• アプリケーション：IF
• 交差性：Human
• 宿主：Rabbit
• アイソタイプ：IgG
• 抗原：Recombinant fusion protein of human LRP6 (NP_002327.2).
• 緩衝液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• 精製方法：Affinity purification
• 希釈倍率：IF 1:50-1:200
• 標識：Unconjugated
• メーカーマニュアル：https://file.elabscience.com/viewpdf-389666-Elabscience-E-AB-66414.pdf
• サイズ：60uL
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