86-3945-99　［取扱停止］PLOD2 Polyclonal Antibody 60uL　E-AB-66203

特徴

• 背景：The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.

仕様

• 抗体タイプ：Polyclonal Antibody
• アプリケーション：IF
• 交差性：Human
• 宿主：Rabbit
• アイソタイプ：IgG
• 抗原：Recombinant fusion protein of human PLOD2 (NP_891988.1).
• 緩衝液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• 精製方法：Affinity purification
• 希釈倍率：IF 1:50-1:100
• 標識：Unconjugated
• メーカーマニュアル：https://file.elabscience.com/viewpdf-389455-Elabscience-E-AB-66203.pdf
• サイズ：60uL
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