86-3944-47　［取扱停止］IL12RB1 Polyclonal Antibody 60uL　E-AB-66049

特徴

• 背景：The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants.

仕様

• 抗体タイプ：Polyclonal Antibody
• アプリケーション：IHC,IF
• 交差性：Human,Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 抗原：Recombinant fusion protein of human IL12RB1 (NP_714912.1).
• 緩衝液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• 精製方法：Affinity purification
• 希釈倍率：IHC 1:50-1:200 IF 1:50-1:200
• 標識：Unconjugated
• メーカーマニュアル：https://file.elabscience.com/viewpdf-389301-Elabscience-E-AB-66049.pdf
• サイズ：60uL
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