86-3941-07　［取扱停止］PE/Cyanine5 Anti-Mouse CD22 Antibody[Cy34.1] 50ug　E-AB-F1021UG

特徴

• 背景：The Cy34.1 monoclonal antibody specifically binds to the B-lymphocyte differentiation antigen CD22 on strains having the Lyb-8.2 alloantigen (e.g., A, BALB/c, CBA, C3H/He, C57BL, C57L, C58, SJL, SWR, but not AKR, DBA/1, DBA/2, NZB, PL). CD22 is expressed at high levels on mature peripheral B lymphocytes (follicular and marginal zone), B-1 cells (CD5+ B cells), and plasma cells. It is a member of the Ig gene superfamily and associates with the B-cell antigen receptor. Its sialic acid- binding immunoglobulin-like lectin (siglec) extracellular region mediates B-cell adhesion to ligands on endothelial cells in the bone marrow. Its intracellular domain is phosphorylated after cross-linking of antigen receptor or MHC class II antigen. It is involved in negative regulation of B-cell activation and protection from autoimmunity. B-cell proliferative responses to LPS or anti-mouse Ig chain are augmented in the presence of Cy34.1 mAb.

仕様

• 抗体タイプ：FC_Antibody
• アプリケーション：FCM
• 交差性：Mouse
• 宿主：Mouse
• アイソタイプ：Mouse IgG1, kappa
• 緩衝液：PBS with 0.05% Proclin300, 1% BSA
• 標識：PE/Cyanine5
• クローナリティ：Monoclonal
• メーカーマニュアルリンク：https://file.elabscience.com/viewpdf-192964-Elabscience-E-AB-F1021UG.pdf
• サイズ：50ug
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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