PAI-1 Reporter （Luc）-Mv1 Lu cell line is designed for monitoring transforming growth factor β （TGF-β）-induced plasminogen activator inhibitor-1 （PAI-1） expression. Transforming growth factor-β （TGF-β） is a potent regulator of cellular differentiation, proliferation, migration, and protein expression.PAI-1 Reporter （Luc） –Mv1 Lu cell line contains a firefly luciferase gene under the control of PAI-1 responsive elements stably integrated into Mv1 Lu （NBL-7） cells, showing TGF-β pathway response. This cell line is validated for the TGF-β response to the induction of PAI-1 gene expression through luciferase activity.
