Recombinant HEK293 cell line expressing full length human CD40 （Tumor necrosis factor receptor superfamily member 5; TNFRSF5）. Expression is confirmed by real-time qPCR and Western Blot. This NF-ĸB luciferase reporter construct is stably integrated into the genome. The firefly luciferase gene is controlled by 4 copies of NF-＆amp;kappa;B response element located upstream of the TATA promoter. Following activation by human CD40 ligand, NF-ĸB transcription factor binds to the DNA response elements to induce transcription of the luciferase gene.
