Established from a squamous cell carcinoma （SCC） of the tongue （20mm） of a 74 year-old male patient. STNMP stage I, well differentiated, node negative tumour. Mutant p53, codon 110 exon 4, G to A; the previously reported mutant Ha-ras status of this cell line： codon： 13, G to A, codon 61, A-G is under investigation. This cell line is highly responsive to TGF （Transforming growth factor ）-β and undergoes epithelial to mesenchymal transition. It expresses high levels of TGF-β1. Fahey et al （1996）. Tumourigenic in athymic nude mice on subcutaneous injection and non-tumorigenic on orthotopic injection. Haplotype information： A*02,A*31; B*40,B*44; Cw*03,Cw*05
