特異性：Rabbit RLA-DQ alpha chain (Mr ~35 kDa) MAb 2C4 reacts with RLA-DQ-transfected cells, but not with RLA-DR-transfected cells2. In normal adult rabbits, the antibody reacts with 30-60% of peripheral blood leukocytes.2,3 It has also been reported that the antibody stains: lymphocytes and macrophages in the spleen; lymphocytes in the thymic medulla and some cells in the cortex; Kupffer cells in the liver; and synovial lining cells (i.e., infiltrating macrophages) in inflamed synovium.4 DQ alpha transcripts have been detected in bone marrow and spleen and, to a lesser extent, in appendix, lymph nodes, and other organs.5
