86-1911-01　Mouse Monoclonal [clone 1H7] (IgG1) to Human IGF1R / IGF1 Receptor 0.05 mg　MBS245289

仕様

• サイズ：0.05 mg
• 遺伝子名：[IGF1R]
• クローナリティ：Monoclonal
• アイソタイプ：IgG1
• クローン名：[1H7]
• ホスト：Mouse
• 反応性：Human
• 特異性：Recognizes human CD221, a 155kD receptor tyrosine kinase, also known as Insulin-like growth factor I receptor (IGF-I Receptor). CD221 is composed of two extracellular alpha-subunits and two transmembrane beta-subunits. Recognizes an epitope in the alpha subunits of CD221, demonstrated by Western blotting. CD221 is expressed in a range of tissues, including kidney, liver, placenta, mammary gland, brain, ovary and skin. The ligands for CD221 include IGF-I and IGF-II, which bind to CD221 and activate tyrosine kinase activity, resulting in phosphorylation of several intracellular signalling proteins. Clone 1H7 is reported to partially block binding of IGF-I and IGF-II to CD221
• 純度：Protein G Purified
• 形状：PBS, pH 7.4, 0.09% sodium azide.
• 濃度：1 mg/ml
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