反応性：Bovine (Expected from Sequence), Dog (Expected from Sequence), Mouse (Expected from Sequence), Rat (Expected from Sequence)
特異性：This item specifically recognises human PI3-kinase p110 subunit alpha (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha), otherwise known as PIK3CA, a member of the PI3/PI4-kinase family of lipid kinases, implicated in the regulation of signal transduction during cell growth. PI3-kinase is a heterodimer consisting of a p85 regulatory subunit and a p110 catalytic subunit, which itself is divided into isoforms p110alpha, p110beta, p110delta and p110gamma. Studies have shown that defects in p110alpha are associated with breast, colorectal and ovarian cancers.
