反応性：Mouse (Expected from Sequence), Rabbit (Expected from Sequence), Rat (Expected from Sequence)
特異性：This item specifically recognises an epitope within the C-terminal (CT) region of human p70S6K, otherwise known as RPS6KB1 (Ribosomal protein S6 kinase beta-1), a serine/threonine kinase which acts upon 40S ribosomal protein S6 to induce protein synthesis, allowing for efficient G1 phase progression. p70S6K is activated following phosphorylation of several sites, in response to hormones, growth factors, mitogenic stimuli and physical exercise, and is a downstream effector in the AKT/mTOR (mammalian target of rapamycin) signalling pathway. Studies have implicated that as well as its role in translation, p70S6K acts as a regulator of cell motility, invasion, and cytoskeletal reorganization.
