反応性:Bovine (Expected from Sequence), Chicken (Expected from Sequence), Dog (Expected from Sequence), Human, Monkey (Expected from Sequence), Mouse (Expected from Sequence), Xenopus (Expected from Sequence), Zebrafish (Expected from Sequence)
特異性:This item is specific for the ~42-44 kDa extracellular-signal regulated kinase/mitogen activated protein kinase (ERK/MAPK), when phosphorylated at threonine 202 and tyrosine 204. ERK/MAPK is an important integration point of many signalling pathways, for a range of cellular processes including proliferation, differentiation, transcription regulation and development. Upon phosphorylation, activated ERK/MAPK translocates to the nucleus, where it phosphorylates nuclear targets.